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GWABLUP: genome-wide association assisted best linear unbiased prediction of genetic values.

Genetics, selection, evolution : GSE - 1 Mar 2024

Meuwissen Theo, Eikje Leiv Sigbjorn, Gjuvsland Arne B

Abstract excerpt

BACKGROUND: Since the very beginning of genomic selection, researchers investigated methods that improved upon SNP-BLUP (single nucleotide polymorphism best linear unbiased prediction). SNP-BLUP gives equal weight to all SNPs, whereas it is expected that many SNPs are not near causal variants and thus do not have substantial effects. A recent approach to remedy this is to use genome-wide association study (GWAS)...

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PMID: 38429665
DOI: 10.1186/s12711-024-00881-y
PMCID: PMC11234632

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