Article
Accounting for trait architecture in genomic predictions of US Holstein cattle using a weighted realized relationship matrix.
Genetics, selection, evolution : GSE - 2 Apr 2015
Tiezzi Francesco, Maltecca Christian
Abstract excerpt
BACKGROUND: Genomic BLUP (GBLUP) can predict breeding values for non-phenotyped individuals based on the identity-by-state genomic relationship matrix (G). The G matrix can be constructed from thousands of markers spread across the genome. The strongest assumption of G and consequently of GBLUP is that all markers contribute equally to the genetic variance of a trait. This assumption is violated for traits that...
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