Article
Genomic BLUP decoded: a look into the black box of genomic prediction.
Genetics - 1 Jul 2013
Habier David, Fernando Rohan L, Garrick Dorian J
Abstract excerpt
Genomic best linear unbiased prediction (BLUP) is a statistical method that uses relationships between individuals calculated from single-nucleotide polymorphisms (SNPs) to capture relationships at quantitative trait loci (QTL). We show that genomic BLUP exploits not only linkage disequilibrium (LD) and additive-genetic relationships, but also cosegregation to capture relationships at QTL. Simulations were used...
Topics
- Animals
- Bayes Theorem
- Breeding
- Genome
- Humans
- Linkage Disequilibrium
- Models, Genetic
- Models, Theoretical
- Multifactorial Inheritance
- Phenotype
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Sample Size
- Zea mays