Weighted single-step genomic BLUP improves accuracy of genomic breeding values for protein content in French dairy goats: a quantitative trait influenced by a major gene.

Abstract excerpt

BACKGROUND: In 2017, genomic selection was implemented in French dairy goats using the single-step genomic best linear unbiased prediction (ssGBLUP) method, which assumes that all single nucleotide polymorphisms explain the same fraction of genetic variance. However, ssGBLUP is not suitable for protein content, which is controlled by a major gene, i.e. α s 1 casein. This gene explains about 40% of the genetic...

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