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Article

Efficient weighting methods for genomic best linear-unbiased prediction (BLUP) adapted to the genetic architectures of quantitative traits.

Heredity - 1 Feb 2021

Ren Duanyang, An Lixia, Li Baojun, Qiao Liying, Liu Wenzhong

Abstract excerpt

Genomic best linear-unbiased prediction (GBLUP) assumes equal variance for all marker effects, which is suitable for traits that conform to the infinitesimal model. For traits controlled by major genes, Bayesian methods with shrinkage priors or genome-wide association study (GWAS) methods can be used to identify causal variants effectively. The information from Bayesian/GWAS methods can be used to construct the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32980863
DOI: 10.1038/s41437-020-00372-y
PMCID: PMC8027853

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