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Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis, and beyond

29 Feb 2024

Abstract excerpt

Cell death resistance represents a hallmark of cancer. Recent studies have identified metabolic cell death as unique forms of regulated cell death resulting from an imbalance in the cellular metabolism. This review discusses the mechanisms of metabolic cell death-ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis-and explores their potential in cancer therapy. Our review underscores the...

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PMID: 38428031
DOI: 10.1093/procel/pwae003

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