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Ferroptosis, a new form of cell death, and its relationships with tumourous diseases

10 Nov 2016

Abstract excerpt

Abstract Ferroptosis is a newly discovered type of cell death that differs from traditional apoptosis and necrosis and results from iron‐dependent lipid peroxide accumulation. Ferroptotic cell death is characterized by cytological changes, including cell volume shrinkage and increased mitochondrial membrane density. Ferroptosis can be induced by two classes of small‐molecule substances known as class 1 (system...

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PMID: 27860262
DOI: 10.1111/jcmm.13008

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