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Cell death and cancer: Metabolic interconnections

1 Jun 2025

Abstract excerpt

Recent findings in the cell death field have transformed our understanding of the interplay between metabolism and cell death in the context of cancer. In this review, we discuss the relationships between metabolism and the cell death pathways of apoptosis, necroptosis, pyroptosis, and ferroptosis, with a particular focus on recent advancements. We will also explore the regulation of metabolism by the BCL-2...

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PMID: 40489330
DOI: 10.1016/j.celrep.2025.115804

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