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Article

Elevated incidence of somatic mutations at prevalent genetic sites.

Briefings in bioinformatics - 22 Jan 2024

Wang Mengyao, Li Shuai Cheng, Shen Bairong

Abstract excerpt

The common loci represent a distinct set of the human genome sites that harbor genetic variants found in at least 1% of the population. Small somatic mutations occur at the common loci and non-common loci, i.e. csmVariants and ncsmVariants, are presumed with similar probabilities. However, our work revealed that within the coding region, common loci constituted only 1.03% of all loci, yet they accounted for 5.14%...

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Identifiers

PMID: 38426321
DOI: 10.1093/bib/bbae065
PMCID: PMC10939422

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