Article
On the genetic basis of tail-loss evolution in humans and apes.
Nature - 1 Feb 2024
Xia Bo, Zhang Weimin, Zhao Guisheng, Zhang Xinru, Bai Jiangshan, Brosh Ran, Wudzinska Aleksandra, Huang Emily, Ashe Hannah, Ellis Gwen, Pour Maayan, Zhao Yu, Coelho Camila, Zhu Yinan, Miller Alexander, Dasen Jeremy S, Maurano Matthew T, Kim Sang Y, Boeke Jef D, Yanai Itai
Abstract excerpt
The loss of the tail is among the most notable anatomical changes to have occurred along the evolutionary lineage leading to humans and to the 'anthropomorphous apes'1-3, with a proposed role in contributing to human bipedalism4-6. Yet, the genetic mechanism that facilitated tail-loss evolution in hominoids remains unknown. Here we present evidence that an individual insertion of an Alu element in the genome of...
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