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Article

Oct4 Is a Key Regulator of Vertebrate Trunk Length Diversity.

Developmental cell - 8 Aug 2016

Aires Rita, Jurberg Arnon D, Leal Francisca, Nóvoa Ana, Cohn Martin J, Mallo Moisés

Abstract excerpt

Vertebrates exhibit a remarkably broad variation in trunk and tail lengths. However, the evolutionary and developmental origins of this diversity remain largely unknown. Posterior Hox genes were proposed to be major players in trunk length diversification in vertebrates, but functional studies have so far failed to support this view. Here we identify the pluripotency factor Oct4 as a key regulator of trunk length...

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Identifiers

PMID: 27453501
DOI: 10.1016/j.devcel.2016.06.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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