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Article

Unique Spectrum of Activating BRAF Alterations in Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 2 Oct 2023

Chehrazi-Raffle Alex, Tukachinsky Hanna, Toye Eamon, Sivakumar Smruthy, Schrock Alexa B, Bergom Hannah E, Ebrahimi Hedyeh, Pal Sumanta, Dorff Tanya, Agarwal Neeraj, Mahal Brandon A, Oxnard Geoffrey R, Hwang Justin, Antonarakis Emmanuel S

Abstract excerpt

PURPOSE: Alterations in BRAF have been reported in 3% to 5% of prostate cancer, although further characterization is lacking. Here, we describe the nature of BRAF alterations in prostate cancer using a large cohort from commercially available tissue and liquid biopsies subjected to comprehensive genomic profiling (CGP). EXPERIMENTAL DESIGN: Tissue and liquid biopsies from patients with prostate cancer were...

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Identifiers

PMID: 37477913
DOI: 10.1158/1078-0432.CCR-23-1393
PMCID: PMC10543965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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