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Article

PIN-like ductal carcinoma of the prostate has frequent activating RAS/RAF mutations.

Histopathology - 1 Jan 2021

Kaur Harsimar B, Salles Daniela C, Paulk Adina, Epstein Jonathan I, Eshleman James R, Lotan Tamara L

Abstract excerpt

AIMS: Prostatic intraepithelial neoplasia-like (PIN-like) ductal carcinoma is a rare tumour characterised by often cystically dilated glands architecturally resembling high-grade PIN, but lacking basal cells. These tumours are frequently accompanied by grade group 1 acinar cancer and behave relatively indolently. In contrast, conventional ductal adenocarcinoma of the prostate is an aggressive variant comparable...

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Identifiers

PMID: 32740981
DOI: 10.1111/his.14224
PMCID: PMC7775281

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