Germline Pathogenic Variants in Squamous Cell Carcinoma of the Head and Neck.

doi:10.14712/fb2023069040107

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Article

Germline Pathogenic Variants in Squamous Cell Carcinoma of the Head and Neck.

Folia biologica - 1 Jan 2023

Drbohlavová Tereza, Argalácsová Soňa, Soukupová Jana, Vočka Michal

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) presents a significant global health problem with variable geographic distribution and risk factors, including tobacco and alcohol abuse, human papillomavirus infections, and genetic predisposition. While the majority of cases are sporadic, several well-defined hereditary syndromes have been associated with a higher risk of developing HNSCC including Li-Fraumeni...

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PMID: 38410968
DOI: 10.14712/fb2023069040107

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