Article
Germline Genetic Testing in Unselected Squamous and Non-Squamous Head and Neck Cancers.
The Laryngoscope - 1 Dec 2023
Brake Daniela A, Idler Beau M, Kunze Katie L, Golafshar Michael A, Heald Brandie, Young Sarah, Klint Margaret, Barrus Kathleen, Esplin Edward D, Nussbaum Robert L, Samadder N Jewel, Hinni Michael L, Chang Brent A
Abstract excerpt
OBJECTIVE: This study describes the prevalence of pathogenic germline variants (PGVs) in head and neck cancer patients, the incremental yield compared to a guideline-based approach to genetic evaluation, and the uptake of family variant testing. STUDY DESIGN: Prospective cohort study. SETTING: Three tertiary academic medical centers. METHODS: Germline sequencing using an 84-gene screening platform among...
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