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Article

Variability in competitive fitness among environmental and clinical azole-resistant Aspergillus fumigatus isolates.

mBio - 10 Apr 2024

Chen Shu, Zhu Guoxing, Lin Huiping, Guo Jian, Deng Shuwen, Wu Wenjuan, Goldman Gustavo H, Lu Ling, Zhang Yuanwei

Abstract excerpt

Azoles are the primary antifungal drugs used to treat infections caused by Aspergillus fumigatus. However, the emergence of azole resistance in A. fumigatus has become a global health concern despite the low proportion of resistant isolates in natural populations. In bacteria, antibiotic resistance incurs a fitness cost that renders strains less competitive in the absence of antibiotics. Consequently, fitness...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38407058
DOI: 10.1128/mbio.00263-24
PMCID: PMC11005360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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