Article
The genetic regulation of the gastric transcriptome is associated with metabolic and obesity-related traits and diseases.
Physiological genomics - 1 May 2024
Koebbe Laura L, Hess Timo, Giel Ann-Sophie, Bigge Jessica, Gehlen Jan, Schueller Vitalia, Geppert Michael, Dumoulin Franz Ludwig, Heller Joerg, Schepke Michael, Plaßmann Dominik, Vieth Michael, Venerito Marino, Schumacher Johannes, Maj Carlo
Abstract excerpt
Tissue-specific gene expression and gene regulation lead to a better understanding of tissue-specific physiology and pathophysiology. We analyzed the transcriptome and genetic regulatory profiles of two distinct gastric sites, corpus and antrum, to identify tissue-specific gene expression and its regulation. Gastric corpus and antrum mucosa biopsies were collected during routine gastroscopies from up to 431...
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