Article
Deciphering genetic regulation at single-cell resolution in gastric cancer.
Cell genomics - 9 Apr 2025
Chen Chengxuan, Han Leng
Abstract excerpt
Understanding cell-type-specific genetic regulation in gastric cancer is essential for uncovering disease susceptibility. By performing single-cell eQTL mapping in gastric tissues, Bian et al.1 identified previously uncharacterized regulatory genetic mechanisms, risk genes, and co-localization signals associated with gastric cancer susceptibility, providing insights into its pathogenesis and potential therapeutic...
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