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Article

Molecular classification as prognostic factor and guide for treatment decision of pancreatic cancer.

Biochimica et biophysica acta. Reviews on cancer - 1 Apr 2018

Birnbaum David J, Bertucci François, Finetti Pascal, Birnbaum Daniel, Mamessier Emilie

Abstract excerpt

Clinico-pathological factors fail to consistently predict the outcome after pancreatic resection for pancreatic ductal adenocarcinoma (PDAC). PDACs show a high level of inter- and intra- tumor genetic heterogeneity. A molecular classification should help sort patients into less heterogeneous and more appropriate groups regarding the metastatic risk and the therapeutic response, with the consequences of better...

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PMID: 29499330
DOI: 10.1016/j.bbcan.2018.02.001

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