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Article

Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal.

Viruses - 17 Apr 2024

Pimentel Victor, Pingarilho Marta, Sebastião Cruz S, Miranda Mafalda, Gonçalves Fátima, Cabanas Joaquim, Costa Inês, Diogo Isabel, Fernandes Sandra, Costa Olga, Corte-Real Rita, Martins M Rosário O, Seabra Sofia G, Abecasis Ana B, Gomes Perpétua

Abstract excerpt

BACKGROUND: The global scale-up of antiretroviral treatment (ART) offers significant health benefits by suppressing HIV-1 replication and increasing CD4 cell counts. However, incomplete viral suppression poses a potential threat for the emergence of drug resistance mutations (DRMs), limiting ART options, and increasing HIV transmission. OBJECTIVE: We investigated the patterns of transmitted drug resistance (TDR)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38675962
DOI: 10.3390/v16040622
PMCID: PMC11054263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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