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Article

Screening for Rare Mitochondrial Genome Variants Reveals a Potentially Novel Association between MT-CO1 and MT-TL2 Genes and Diabetes Phenotype.

International journal of molecular sciences - 19 Feb 2024

Płoszaj Tomasz, Skoczylas Sebastian, Gadzalska Karolina, Jakiel Paulina, Juścińska Ewa, Gorządek Monika, Robaszkiewicz Agnieszka, Borowiec Maciej, Zmysłowska Agnieszka

Abstract excerpt

Variations in several nuclear genes predisposing humans to the development of MODY diabetes have been very well characterized by modern genetic diagnostics. However, recent reports indicate that variants in the mtDNA genome may also be associated with the diabetic phenotype. As relatively little research has addressed the entire mitochondrial genome in this regard, the aim of the present study is to evaluate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38397113
DOI: 10.3390/ijms25042438
PMCID: PMC10889583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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