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Article

Next-generation sequencing profiling of mitochondrial genomes in gout.

Arthritis research & therapy - 6 Jul 2018

Tseng Chia-Chun, Chen Chung-Jen, Yen Jeng-Hsien, Huang Hsi-Yuan, Chang Jan-Gowth, Chang Shun-Jen, Liao Wei-Ting

Abstract excerpt

BACKGROUND: Accumulating evidence implicates mitochondrial DNA (mtDNA) alleles, which are independent of the nuclear genome, in disease, especially in human metabolic diseases. However, this area of investigation has lagged behind in researching the nuclear alleles in complex traits, for example, in gout. METHODS: Next-generation sequencing was utilized to investigate the relationship between mtDNA alleles and...

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Identifiers

PMID: 29976239
DOI: 10.1186/s13075-018-1637-5
PMCID: PMC6034246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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