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Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2

13 Feb 2024

Abstract excerpt

The identification of surfaceome proteins is a main goal in cancer research to design antibody-based therapeutic strategies. T cell engagers based on KLK2, a kallikrein specifically expressed in prostate cancer (PRAD), are currently in early clinical development. Using genomic information from different sources, we evaluated the immune microenvironment and genomic profile of prostate tumors with high expression...

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PMID: 38396898
DOI: 10.3390/ijms25042222

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