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Article

Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer.

The Prostate - 1 Sept 2020

Bonk Sarah, Kluth Martina, Jansen Kristina, Hube-Magg Claudia, Makrypidi-Fraune Georgia, Höflmayer Doris, Weidemann Sören, Möller Katharina, Uhlig Ria, Büscheck Franziska, Luebke Andreas M, Burandt Eike, Clauditz Till S, Steurer Stefan, Schlomm Thorsten, Huland Hartwig, Heinzer Hans, Sauter Guido, Simon Ronald, Dum David

Abstract excerpt

BACKGROUND: Kallikrein-related peptidase 2 (KLK2)-like KLK3 (prostate-specific antigen [PSA])-belongs to the highly conserved serine proteases of the glandular kallikrein protein family (KLK family). Studies suggested that measurement of KLK2 serum levels advanced the predictive accuracy of PSA testing in prostate cancer. METHODS: To clarify the potential utility of KLK2 as a prognostic tissue biomarker, KLK2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32628300
DOI: 10.1002/pros.24038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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