Article
SARS-CoV-2 Infection Alters the Phenotype and Gene Expression of Adipocytes.
International journal of molecular sciences - 8 Feb 2024
Quaranta Paola, Scabia Gaia, Storti Barbara, Dattilo Alessia, Quintino Lara, Perrera Paola, Di Primio Cristina, Costa Mario, Pistello Mauro, Bizzarri Ranieri, Maffei Margherita
Abstract excerpt
Epidemiological evidence emphasizes that excess fat mass is associated with an increased risk of severe COVID-19 disease. Nevertheless, the intricate interplay between SARS-CoV-2 and adipocytes remains poorly understood. It is crucial to decipher the progression of COVID-19 both in the acute phase and on long-term outcomes. In this study, an in vitro model using the human SGBS cell line (Simpson-Golabi-Behmel...
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