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Article

Simpson-Golabi-Behmel syndrome human adipocytes reveal a changing phenotype throughout differentiation.

Histochemistry and cell biology - 1 Jun 2018

Montanari T, Colitti M

Abstract excerpt

The Simpson-Golabi-Behmel syndrome (SGBS) cell strain is widely considered to be a representative in vitro model of human subcutaneous white pre-adipocytes. These cells achieve a transient expression of classical brown markers, such as uncoupling protein 1, peaking at day 14 of differentiation and decreasing thereafter. Adipocyte browning process involves dynamic changes in lipid droplet (LD) dimension, in...

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PMID: 29574488
DOI: 10.1007/s00418-018-1663-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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