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Article

SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner

29 Sept 2022

Abstract excerpt

Visceral adiposity is a risk factor for severe COVID-19, and a link between adipose tissue infection and disease progression has been proposed. Here we demonstrate that SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells. However, susceptibility to infection and the cellular response depends on the anatomical origin of the cells and the viral lineage. Visceral fat cells express...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 36175400
DOI: 10.1038/s41467-022-33218-8

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