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Article

Identification and In-Silico study of non-synonymous functional SNPs in the human SCN9A gene.

PloS one - 1 Jan 2024

Waheed Sana, Ramzan Kainat, Ahmad Sibtain, Khan Muhammad Saleem, Wajid Muhammad, Ullah Hayat, Umar Ali, Iqbal Rashid, Ullah Riaz, Bari Ahmed

Abstract excerpt

Single nucleotide polymorphisms are the most common form of DNA alterations at the level of a single nucleotide in the genomic sequence. Genome-wide association studies (GWAS) were carried to identify potential risk genes or genomic regions by screening for SNPs associated with disease. Recent studies have shown that SCN9A comprises the NaV1.7 subunit, Na+ channels have a gene encoding of 1988 amino acids...

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Identifiers

PMID: 38394191
DOI: 10.1371/journal.pone.0297367
PMCID: PMC10889873

Genes

SCN9A

Variants

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