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Serum MYCN as a predictive biomarker of prognosis and therapeutic response in the prevention of hepatocellular carcinoma recurrence

21 Feb 2024

Abstract excerpt

The proto-oncogene MYCN expression marked a cancer stem-like cell population in hepatocellular carcinoma (HCC) and served as a therapeutic target of acyclic retinoid (ACR), an orally administered vitamin A derivative that has demonstrated promising efficacy and safety in reducing HCC recurrence. This study investigated the role of MYCN as a predictive biomarker for therapeutic response to ACR and prognosis of...

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Share to Endoplasmic Reticulum Stress and Disease
Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Liver Disease Diagnosis and Treatment

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PMID: 38380807
DOI: 10.1002/ijc.34893

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