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METTL14 affects UVB ‐induced human dermal fibroblasts photoaging via miR ‐100‐3p biogenesis in an m6A ‐dependent manner

21 Feb 2024

Abstract excerpt

Abstract Exposure to ultraviolet radiation can lead to skin photoaging, which increases the risk of skin tumors. This study aims to investigate how microRNA m6A modification contributes to skin photoaging. This study found that skin fibroblasts exposed to a single UVB dose of 30 mJ/cm2 exhibited characteristics of photoaging. The m6A level of total RNA decreased in photoaged cells with a down‐regulated level of...

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PMID: 38380598
DOI: 10.1111/acel.14123

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