Article

Extracellular vesicles derived from human dermal fibroblast effectively ameliorate skin photoaging via miRNA-22-5p-GDF11 axis

2022-10-06

Abstract excerpt

Aging is the leading cause of several degenerative diseases. Photoaging due to ultraviolet (UV) exposure accounts for more than 80% of facial aging, which is a complex and incompletely understood process. Here, we explored the mechanisms of skin photoaging and increased chromatin accessibility in UVB-irradiated human dermal fibroblasts (UVB-HDFs). Especially, we investigated key skin photoaging pathways and inflam...

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Literature Corpus work: 68d2a90b-04d4-5dc8-b1f2-e4050efea1bb
DOI: 10.1016/j.cej.2022.139553

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