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DNA methylome and transcriptome alterations and cancer prevention by triterpenoid ursolic acid in UVB‐induced skin tumor in mice

25 Jun 2019

Abstract excerpt

Nonmelanoma skin cancers (NMSCs) are the most common type of skin cancers. Major risk factors for NMSCs include exposure to ultraviolet (UV) irradiation. Ursolic acid (UA) is a natural triterpenoid enriched in blueberries and herbal medicinal products, and possess anticancer activities. This study focuses on the impact of UA on epigenomic, genomic mechanisms and prevention of UVB-mediated NMSC. CpG methylome and...

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PMID: 31237383
DOI: 10.1002/mc.23046

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