Processing speed mediates the relationship between DDR1 and psychosocial functioning in euthymic patients with bipolar disorder presenting psychotic symptoms.

doi:10.1038/s41380-024-02480-1

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Article

Processing speed mediates the relationship between DDR1 and psychosocial functioning in euthymic patients with bipolar disorder presenting psychotic symptoms.

Molecular psychiatry - 1 Jul 2024

Aranda Selena, Jiménez Esther, Canales-Rodríguez Erick J, Verdolini Norma, Alonso Silvia, Sepúlveda Esteban, Julià Antonio, Marsal Sara, Bobes Julio, Sáiz Pilar A, García-Portilla Paz, Menchón Jose M, Crespo José M, González-Pinto Ana, Pérez Víctor, Arango Celso, Sierra Pilar, Sanjuán Julio, Pomarol-Clotet Edith, Vieta Eduard, Vilella Elisabet

Abstract excerpt

The DDR1 locus is associated with the diagnosis of schizophrenia and with processing speed in patients with schizophrenia and first-episode psychosis. Here, we investigated whether DDR1 variants are associated with bipolar disorder (BD) features. First, we performed a case‒control association study comparing DDR1 variants between patients with BD and healthy controls. Second, we performed linear regression...

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PMID: 38374360
DOI: 10.1038/s41380-024-02480-1

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DDR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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