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Article

Genetic variants in the ErbB4 gene are associated with white matter integrity.

Psychiatry research - 28 Feb 2011

Zuliani Riccardo, Moorhead T William J, Bastin Mark E, Johnstone Eve C, Lawrie Stephen M, Brambilla Paolo, O'Donovan Michael C, Owen Michael J, Hall Jeremy, McIntosh Andrew M

Abstract excerpt

Variations in the signalling NRG1-ErbB4 pathway have been associated with genetic susceptibility for both bipolar disorder and schizophrenia, although the underlying neural mechanisms are still uncertain. Reduced integrity of the anterior limb of the internal capsule (ALIC) has been found in association with risk-associated genetic variation in the 5' region of the NRG1 gene. We hypothesised that variation in the...

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Identifiers

PMID: 21232925
DOI: 10.1016/j.pscychresns.2010.11.001
PMCID: PMC5372351

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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