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Article

Next-generation direct reprogramming

2 Feb 2024

Abstract excerpt

Tissue repair is significantly compromised in the aging human body resulting in critical disease conditions (such as myocardial infarction or Alzheimer's disease) and imposing a tremendous burden on global health. Reprogramming approaches (partial or direct reprogramming) are considered fruitful in addressing this unmet medical need. However, the efficacy, cellular maturity and specific targeting are still major...

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PMID: 38371924
DOI: 10.3389/fcell.2024.1343106

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