Article
MET alterations in NSCLC-Current Perspectives and Future Challenges.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2023
Remon Jordi, Hendriks Lizza E L, Mountzios Giannis, García-Campelo Rosario, Saw Stephanie P L, Uprety Dipesh, Recondo Gonzalo, Villacampa Guillermo, Reck Martin
Abstract excerpt
Targeted therapies have revolutionized the treatment and improved the outcome for oncogene-driven NSCLC and an increasing number of oncogenic driver therapies have become available. For MET-dysregulated NSCLC (especially MET exon 14 skipping mutations and MET-amplifications, which is one of the most common bypass mechanisms of resistance in oncogene-addicted NSCLC), several anti-MET-targeted therapies have been...
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