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Application of Northern Goshawk Back-Propagation Artificial Neural Network in the Prediction of Monohydroxycarbazepine Concentration in Patients with Epilepsy.

Advances in therapy - 1 Apr 2024

Xu Yichao, Shao Rong, Yang Mingdong, Chen Meng, Xu Junjun, Dai Haibin

Abstract excerpt

INTRODUCTION: A northern goshawk back-propagation artificial neural network (NGO-BPANN) model was established to predict monohydroxycarbazepine (MHD) concentration in patients with epilepsy. METHODS: The data were collected from 108 Han Chinese patients with epilepsy on oxcarbazepine monotherapy. The results of 14 genotype variates were selected as the input layer in the first BPANN model, and the variables that...

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PMID: 38358607
DOI: 10.1007/s12325-024-02792-2

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