AI vs. population pharmacokinetic models to predict the concentrations of antiepileptic drug using TDM records

Abstract excerpt

<title>Abstract</title> <p>Population pharmacokinetic (PK) models are commonly used to predict drug concentrations, but artificial intelligence (AI) models offer advantages in handling complex patterns without requiring mathematical assumptions. This study compares the predictive performance of AI and population PK models using therapeutic drug monitoring (TDM) records of four antiepileptic drugs (AEDs): carbamaz...

Topics

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• AI in cancer detection
• Bayes Theorem
• Bioinformatics and Genomic Networks
• Computational Drug Discovery Methods
• Cytochrome P-450 CYP3A
• East Asian People
• Immunosuppressive Agents
• Radiomics and Machine Learning in Medical Imaging

Identifiers and source

Literature Corpus work

81d94516-e425-5565-bcbf-9213b658508c

DOI

10.21203/rs.3.rs-6143008/v1