Article
Investigating the shared genetic architecture between COVID-19 and obesity: a large-scale genome wide cross-trait analysis.
Frontiers in endocrinology - 1 Jan 2024
Chen Yanjing, Fan Chunhua, Liu Jun
Abstract excerpt
Observational studies have reported high comorbidity between obesity and severe COVID-19. The aim of this study is to explore whether genetic factors are involved in the co-occurrence of the two traits. Based on the available genome-wide association studies (GWAS) summary statistics, we explored the genetic correlation and performed cross-trait meta-analysis (CPASSOC) and colocalization analysis (COLOC) to detect...
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