Article

Canine idiopathic epilepsy as a natural animal model for human epilepsy: a metabolic perspective beyond the brain

2026-03-09

Abstract excerpt

<title>Abstract</title> <p>Emerging evidence indicates that epilepsy extends beyond the brain, involving systemic metabolic, immune, and microbiome perturbations that shape neuronal excitability and treatment response. Canine idiopathic epilepsy (CE) offers a naturally occurring, genetically diverse model with strong electrophysiological, pharmacological, and clinical homology to human epilepsies. In this review,...

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Literature Corpus work: 6e7cd963-67f5-59a5-902d-c5de5ca0188f
DOI: 10.21203/rs.3.rs-9048832/v1

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