Article
Expression of cell surface zinc transporter LIV1 in triple negative breast cancer is an indicator of poor prognosis and therapy failure.
Journal of cellular physiology - 1 Apr 2024
Saravanan Roshni, Balasubramanian Vaishnavi, Sundaram Sandhya, Dev Bhawna, Vittalraj Pavithra, Pitani Ravi Shankar, Shanmugasundaram Gouthaman, Rayala Suresh Kumar, Venkatraman Ganesh
Abstract excerpt
Triple negative breast cancers (TNBC) are an aggressive molecular subtype of breast carcinoma (BC) identified by the lack of receptor expression for estrogen, progesterone, & human epidermal growth factor receptor-2. Lack of tangible drug targets warrants further research in TNBC. LIV1, is a zinc (Zn) transporter known to be overexpressed in few cancer types including BCs. Recently, in the United States of...
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