Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of Mutational Status of IGHV, and Cytokine Polymorphisms as Prognostic Factors in Chronic Lymphocytic Leukemia: The Romanian Experience.

International journal of molecular sciences - 1 Feb 2024

Balla Beata, Tripon Florin, Lazar Erzsebet, Bănescu Claudia

Abstract excerpt

The aim of the current study was to assess the associations between genetic risk factors (such as the mutational status of the IGHV gene and polymorphisms of the IL-10 and TNF-α genes) and CLL risk, prognosis, and overall survival. Another goal of this study was to evaluate the multivariate effect of the combination of multiple genetic risk factors (mutational status of the IGHV gene, somatic mutations, DNA CNVs,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to Interleukin-10

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Prognosis

Share to Romania

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 38339076
DOI: 10.3390/ijms25031799
PMCID: PMC10855205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of Mutational Status of IGHV, and Cytokine Polymorphisms as Prognostic Factors in Chronic Lymphocytic Leukemia: The Romanian Experience.PMID 38339076Read ↗

Polymorphisms of TNF and IL-10 genes and clinical outcome of patients with chronic lymphocytic leukemia.Semantic proximity Read ↗

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLLSemantic proximity Read ↗

Prognostic impact of genetic abnormalities in 536 first-line chronic lymphocytic leukaemia patients without 17p deletion treated with chemoimmunotherapy in two prospective trials: Focus on IGHV-mutated subgroups (a FILO study).Semantic proximity Read ↗

Clinical and therapeutic implications of the mutational status of IgVH in patients with chronic lymphocytic leukemia.Semantic proximity Read ↗

Serum tumor necrosis factor-α and interleukin-10 levels as markers to predict outcome of patients with chronic lymphocytic leukemia in different risk groups defined by the IGHV mutation status.Semantic proximity Read ↗

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia.Semantic proximity Read ↗

Surrogate molecular markers for IGHV mutational status in chronic lymphocytic leukemia for predicting time to first treatment.Semantic proximity Read ↗

Mutation status and immunoglobulin gene rearrangements in patients from northwest and central region of Spain with chronic lymphocytic leukemia.Semantic proximity Read ↗

ZAP-70, IgVh, and cytogenetics for assessing prognosis in chronic lymphocytic leukemia.Semantic proximity Read ↗

Modern and conventional prognostic markers of chronic lymphocytic leukaemia in the everyday haematological practice.Semantic proximity Read ↗

Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencingSemantic proximity Read ↗

[Mutational features of immunoglobulin heavy chain variable region gene in patients with chronic lymphocytic leukemia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.