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The interaction between DNA methylation and tumor immune microenvironment: from the laboratory to clinical applications

8 Feb 2024

Abstract excerpt

DNA methylation is a pivotal epigenetic modification that affects gene expression. Tumor immune microenvironment (TIME) comprises diverse immune cells and stromal components, creating a complex landscape that can either promote or inhibit tumor progression. In the TIME, DNA methylation has been shown to play a critical role in influencing immune cell function and tumor immune evasion. DNA methylation regulates...

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PMID: 38331927
DOI: 10.1186/s13148-024-01633-x

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