One novel single nucleotide polymorphism c.424A>G on A1.02 allele in ABO glycosyltransferases leads to Aweak phenotype.

doi:10.1016/j.jfma.2024.02.001

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

One novel single nucleotide polymorphism c.424A>G on A1.02 allele in ABO glycosyltransferases leads to Aweak phenotype.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Nov 2024

Lei Hang, Zhang Hui, Wang Yuqing, Li Jiaming, Wang Xuefeng, Lou Can, Cai Xiaohong

Abstract excerpt

BACKGROUND: The dysfunction of the ABO glycosyltransferase (GT) enzyme, which is caused by mutations in the ABO gene, can lead to weak ABO phenotypes. In this study, we have discovered a novel weak ABO subgroup allele and investigated the underlying mechanism to causing its Aweak phenotype. MATERIALS AND METHODS: The ABO phenotyping and genotyping were performed by serological studies and direct DNA sequencing of...

Topics

Humans
ABO Blood-Group System
Alleles
Genotype
Glycosyltransferases
Phenotype
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 38331639
DOI: 10.1016/j.jfma.2024.02.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics