Article
Molecular genetic analysis of weak ABO subgroups in the Chinese population reveals ten novel ABO subgroup alleles.
Blood transfusion = Trasfusione del sangue - 1 May 2019
Huang Haobo, Jin Sha, Liu Xi, Wang Zhongying, Lu Qiong, Fan Liangfeng, Shen Wei, Lei Hang, Qian Chengrui, Wang Xuefeng, Xiang Dong, Cai Xiaohong
Abstract excerpt
BACKGROUND: A weak ABO subgroup is one of the most important causes of an ABO blood grouping discrepancy. Here, we investigated the distribution of weak ABO subgroups in the Chinese population and identified ten novel weak ABO subgroup alleles. MATERIAL AND METHODS: We performed phenotype investigations by serological studies, analysed the DNA sequence of the ABO gene by direct sequencing or sequencing after...
Topics
- ABO Blood-Group System
- Alleles
- Asian People
- DNA Mutational Analysis
- Female
- HeLa Cells
- Humans
- Male
- Mutation