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Molecular genetics and genomics of the ABO blood group system

2021-06-15

Abstract excerpt

The A and B oligosaccharide antigens of the ABO blood group system are produced from the common precursor, H substance, by enzymatic reactions catalyzed by A and B glycosyltransferases (AT and BT) encoded by functional A and B alleles at the ABO genetic locus, respectively. In 1990, my research team cloned human A , B , and O allelic cDNAs. We then demonstrated this central dogma of ABO and opened a new era of mol...

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Literature Corpus work
037388ae-cdf4-5498-b34d-85ddd54af74c
DOI
10.21037/aob-20-71
Open publication

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Molecular genetics and genomics of the ABO blood group systemDOI 10.21037/aob-20-71
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