Article
Bipartite viral RNA genome heterodimerization influences genome packaging and virion thermostability.
Journal of virology - 19 Mar 2024
Zhou Yiyang, Routh Andrew L
Abstract excerpt
Multi-segmented viruses often multimerize their genomic segments to ensure efficient and stoichiometric packaging of the correct genetic cargo. In the bipartite Nodaviridae family, genome heterodimerization is also observed and conserved among different species. However, the nucleotide composition and biological function for this heterodimer remain unclear. Using Flock House virus as a model system, we developed...
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