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Article

Steered molecular dynamics identifies critical residues of the Nodamura virus B2 suppressor of RNAi.

Journal of molecular modeling - 1 Mar 2014

Allen William J, Wiley Michael R, Myles Kevin M, Adelman Zach N, Bevan David R

Abstract excerpt

Nearly all RNA viruses produce double-stranded RNA (dsRNA) during their replication cycles--an important pathogen-associated molecular pattern recognized by the RNA interference (RNAi) pathway in invertebrates and plants. Nodamura virus (NoV) encodes a suppressor of RNA silencing termed B2, which binds to dsRNA and prevents the initiation of RNAi as well as the loading of silencing complexes. Using the published...

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Identifiers

PMID: 24549790
DOI: 10.1007/s00894-014-2092-0
PMCID: PMC5862041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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