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Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population.

Translational psychiatry - 6 Feb 2024

Park Kyungtaek, Do Ah Ra, Chung Yuree, Kim Min Ji, Rhee Sang Jin, Yoon Dae Hyun, Choi Seung Ho, Cho Sung Joon, Kim Han-Na, Ahn Yong Min, Won Sungho

Abstract excerpt

Although depression is an emerging disorder affecting many people worldwide, most genetic studies have been performed in European descent populations. Herein, a genome-wide association study (GWAS) was conducted in Korean population to elucidate the genomic loci associated with depressive symptoms. Two independent cohorts were used as discovery datasets, which consisted of 6474 (1484 cases and 4990 controls) and...

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PMID: 38320993
DOI: 10.1038/s41398-024-02777-3
PMCID: PMC10847124

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