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Article

A sequence-aware merger of genomic structural variations at population scale.

Nature communications - 2 Feb 2024

Zheng Zeyu, Zhu Mingjia, Zhang Jin, Liu Xinfeng, Hou Liqiang, Liu Wenyu, Yuan Shuai, Luo Changhong, Yao Xinhao, Liu Jianquan, Yang Yongzhi

Abstract excerpt

Merging structural variations (SVs) at the population level presents a significant challenge, yet it is essential for conducting comprehensive genotypic analyses, especially in the era of pangenomics. Here, we introduce PanPop, a tool that utilizes an advanced sequence-aware SV merging algorithm to efficiently merge SVs of various types. We demonstrate that PanPop can merge and optimize the majority of...

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Identifiers

PMID: 38307885
DOI: 10.1038/s41467-024-45244-9
PMCID: PMC10837428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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